Fetal Sex, Maternal Race Affect Pregnancy Inflammatory Markers

KPSOM faculty research highlights factors associated with C-reactive protein in early pregnancy

August 03, 2023

KPSOM faculty member Dr. Robert S. Zeiger

KPSOM faculty member Dr. Robert S. Zeiger

Kaiser Permanente Bernard J. Tyson School of Medicine (KPSOM) faculty member Robert S. Zeiger, MD, PhD, has coauthored a study that sheds light on the complex interplay between fetal sex, maternal race, and inflammatory markers during pregnancy. The study examined C-reactive protein (CRP) and interleukin-8 (IL-8) levels in early and late pregnancy, revealing intriguing associations.

According to the findings, women carrying male fetuses had higher CRP levels during early to mid-pregnancy. Moreover, maternal race appeared to play a role, with Hispanic African American (AA) women and women of races other than White and AA exhibiting higher CRP levels in early to mid-pregnancy compared to White women. Furthermore, maternal race/ethnicity seemed to influence the relationship between fetal sex and inflammatory responses during pregnancy.

Read the article here .