William J. Towner, MD, FACP, FIDSA

Associate Professor

Dr. William Towner has been a staff physician with Southern California Permanente Medical Group since 1997, and his work focuses on caring for patients affected by HIV. He has been Principal Investigator for multiple ongoing Phase II and Phase III clinical trials. Dr. Towner is also committed to medical education, which he demonstrated by serving as teaching faculty for the Internal Medicine Residency at the Kaiser Permanente Los Angeles Medical Center, an Assistant Clinical Professor of Medicine at the UCLA School of Medicine, and an Associate Professor at the Kaiser Permanente School of Medicine.

Education and Training

  • BS, with honors, University of California, Los Angeles (UCLA)
  • MS, UCLA Graduate Division
  • MD, University of Southern California School of Medicine
  • Internship, Internal Medicine, Kaiser Permanente Medical Center, San Francisco
  • Residency, Anesthesiology, UCLA Medical Center
  • Residency, Internal Medicine, Kaiser Permanente Medical Center, San Francisco

Years

Selected Prior Positions

1997-present Staff Physician
Southern California Permanente Medical Group (SCPMG)
2013-present Fellow
Infectious Diseases Society of America
2004-present Fellow
American College of Physicians
1999-present Assistant Clinical Professor of Medicine
UCLA School of Medicine
2015-2018 Member
Board of Directors, HIV Medicine Association (IDSA)
2000-present Director
Kaiser Permanente Los Angeles Medical Center HIV Clinic
2004-present Director
HIV Medical Care Program, Kaiser Southern California
2000-present Director and Principal Investigator
Southern California Kaiser Permanente Infectious Disease Clinical Research Program
2014-present Regional Director
Kaiser Permanente Southern California Clinical Trials Program

Years

Selected Honors and Awards

2008 Faculty Research Award
Kaiser Permanente Los Angeles
2008-present Member
Los Angeles County Office of AIDS Programs and Policy Task Force
2009-2012 NCQA Diabetes Care Recognition Award
National Committee for Quality Assurance
2010 Faculty Research Award
Kaiser Permanente Los Angeles
2012-2015 NCQA Diabetes Care Recognition Award
National Committee for Quality Assurance

Selected Publications

Selected peer-reviewed research manuscripts

  • S Naggie, C Cooper, M Saag, K Workowski, P Ruane, W Towner, K Marks, A Luetkemeyer, R Baden, P Sax, E Gane, J Santana-Bagur, L Stamm, J Yang, P German, H Dvory-Sobol, L Ni, P Pang, J McHutchison, C Stedman, J Morales-Ramirez, N Bräu, D Jayaweera, A Colson, P Tebas, D Wong, D Dieterich, M Sulkowski; ION-4 Investigators. Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1. N Engl J Med. 2015 Aug 20;373(8):705-13. Epub 2015 Jul 21. PMID: 26196665
  • G Everson, W Towner, M Davis, D Wyles, R Nahass, P Thuluvath, K Etzkorn, F Hinestrosa, M Tong, M Rabinovitz, J McNally, D Brainard, L Han, B Doehle, J McHutchison, T Morgan, R Chung, T Tran. Sofosbuvir With Velpatasvir in Treatment-Naive Noncirrhotic Patients With Genotype 1 to 6 Hepatitis C Virus Infection: A Randomized Trial. Ann Intern Med. 2015 Nov 10. [Epub ahead of print] PMID: 26551051
  • J Feld, I Jacobson, C Hézode, T Asselah, P Ruane, N Gruener, A Abergel, A Mangia, C Lai, H Chan, F Mazzotta, C Moreno, E Yoshida, S Shafran, W Towner, T Tran, J McNally, A Osinusi, E Svarovskaia, Y Zhu, D Brainard, J McHutchison, K Agarwal, S Zeuzem; ASTRAL-1 Investigators. Sofosbuvir and Velpatasvir for HCV Genotype 1, 2, 4, 5, and 6 Infection. N Engl J Med. 2015 Dec 31;373(27):2599-607.PMID: 26571066
  • G Foster, N Afdhal, S Roberts, N Bräu, E Gane, S Pianko, E Lawitz, A Thompson, M Shiffman, C Cooper, W Towner, B Conway, P Ruane, M Bourlière, T Asselah, T Berg, S Zeuzem, W Rosenberg, K Agarwal, C Stedman, H Mo, H Dvory-Sobol, L Han, J Wang, J McNally, A Osinusi, D Brainard, J McHutchison, F Mazzotta, T Tran, S Gordon, K Patel, N Rea, A Mangia, M Sulkowski; ASTRAL-2 and ASTRAL-3 Investigators. Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection. N Engl J Med. 2015 Dec 31;373(27):2608-17. doi: 10.1056/NEJMoa1512612. Epub 2015 Nov 17
    PMID: 26575258
  • J Marcus, C Chao, W Leyden, L Xu, C Quesenberry Jr, D Klein, W Towner, M Horberg, M Silverberg. Narrowing the Gap in Life Expectancy Between HIV-Infected and HIV-Uninfected Individuals With Access to Care. J Acquir Immune Defic Syndr. 2016 Sep 1;73(1):39-46. PMID: 27028501
  • J Marcus, R Baxter, W Leyden, D Muthulingam, A Yee, M Horberg, D Klein, W Towner, C Chao, C Quesenberry Jr, M Silverberg. Invasive Pneumococcal Disease Among HIV-Infected and HIV-Uninfected Adults in a Large Integrated Healthcare System. AIDS Patient Care STDS. 2016 Oct;30(10):463-470. PMID: 27749111
  • J Marcus, W Leyden, C Chao, M Horberg, D Klein, C Quesenberry Jr, W Towner, M Silverberg. Immunodeficiency, AIDS-related pneumonia, and risk of lung cancer among HIV-infected individuals. AIDS. 2017 Apr 24;31(7):989-993. PMID: 28252529
  • J Wu, K Gilbert, M Batech, I Manalo, W Towner, R Raposo, D Nixon, W Liao. Examining HIV Viral Load in a Matched Cohort of HIV Positive Individuals With and Without Psoriasis. J Drugs Dermatol. 2017 Apr 1;16(4):372-377. PMID: 28403272
  • J Arribas, E DeJesus, J van Lunzen, C Zurawski, M Doroana, W Towner, A Lazzarin, M Nelson, D McColl, K Andreatta, R Swamy, J Szwarcberg, T Nguyen. Simplification to single-tablet regimen of elvitegravir, cobicistat, emtricitabine, tenofovir DF from multi-tablet ritonavir-boosted protease inhibitor plus coformulated emtricitabine and tenofovir DF regimens: week 96 results of STRATEGY-PI. HIV Clin Trials. 2017 May;18(3):118-125. Epub 2017 May 30. PMID:28555519
  • R Hechter, Z Bider-Canfield, W Towner. Effect of an Electronic Alert on Targeted HIV Testing Among High-Risk Populations. Perm J. 2018 Sep 20;22.